• Evaluation of a Bayesian network for strengthening the weight of evidence to predict acute fish toxicity from fish embryo toxicity data 

      Lillicrap, Adam David; Moe, Jannicke; Wolf, Raoul; Connors, Kristin A.; Rawlings, Jane M.; Landis, Wayne G.; Madsen, Anders L.; Belanger, Scott E. (Peer reviewed; Journal article, 2020)
      The use of sh embryo toxicity (FET) data for hazard assessments of chemicals, in place of acute sh toxicity (AFT) data, has long been the goal for many environmental scientists. The FET test was rst proposed as a ...
    • OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing 

      Busquet, François; Strecker, Ruben; Rawlings, Jane M.; Belanger, Scott E.; Braunbeck, Thomas; Carr, Gregory J.; Cenijn, Peter; Fochtman, Przemyslaw; Gourmelon, Anne; Hübler, Nicole; Kleensang, André; Knöbel, Melanie; Kussatz, Carola; Legler, Juliette; Lillicrap, Adam David; Martínez-Jerónimo, Fernando; Polleichtner, Christian; Rzodeczko, Helena; Salinas, Edward; Schneider, Katharina E.; Scholz, Stefan; van den Brandhof, Evert-Jan; van der Ven, Leo T.M.; Walter-Rohde, Susanne; Weigt, Stefan; Witters, Hilda; Halder, Marlies (Journal article; Peer reviewed, 2014)
      The OECD validation study of the zebrafish embryo acute toxicity test (ZFET) for acute aquatic toxicity testing evaluated the ZFET reproducibility by testing 20 chemicals at 5 different concentrations in 3 independent runs ...
    • Repeatability and reproducibility of the RTgill-W1 cell line assay for predicting fish acute toxicity 

      Fischer, Melanie; Belanger, Scott E.; Berckmans, Pascale; Bernhard, Mary J.; Bláha, Ludek; Coman Schmid, Diana E.; Dyer, Scott D.; Haupt, Tina; Hermens, Joop L.M.; Hultman, Maria Thérése; Laue, Heike; Lillicrap, Adam David; Mlnaříková, Marie; Natsch, Andreas; Novák, Jirí; Sinnige, Theo L.; Tollefsen, Knut-Erik; Niederhäusern, Valentin von; Witters, Hilda; Zupanic, Anze; Schirmer, Kristin (Journal article; Peer reviewed, 2019)
      Predicting fish acute toxicity of chemicals in vitro is an attractive alternative method to the conventional approach using juvenile and adult fish. The rainbow trout (Oncorhynchus mykiss) cell line assay with RTgill-W1 ...
    • Weight of evidence tools in the prediction of acute fish toxicity 

      Belanger, Scott E.; Lillicrap, Adam David; Moe, S. Jannicke; Wolf, Raoul; Connors, Kristin; Embry, Michelle R. (Peer reviewed; Journal article, 2022)
      Acute fish toxicity (AFT) is a key endpoint in nearly all regulatory implementations of environmental hazard assessments of chemicals globally. Although it is an early tier assay, the AFT assay is complex and uses many ...